Heaven knows where it came from, but one day we will know. However, the deadly Ebola virus that has attacked our country in the way it has none other, will soon be gone. It is receding fast, as many of the Ebola treatment units (ETUs) are down in patients. Today, according to Dorbor Jallah, Deputy Incident Manager at the anti-Ebola Incident Management System, there are less than 400 Ebola cases nationwide, down from thousands. We must quickly add, however, Mr. Jallah’s warning: “We are not yet out of the woods; therefore it is incumbent on everyone in Liberia to obey strictly all the rules.” Mr. Jallah repeated them to our reporters who interviewed him last Sunday: Don’t touch any infected person. Don’t touch any dead body. Take yourself or anyone else suspected of any of the symptoms—very high fever, vomiting, frequent bleeding or stooling—immediately to a treatment center for testing. Wash your hands on entering or exiting a building. Avoid all cultural or religious practices that could spread the virus. Avoid traveling to other places for now.Why is it important and crucial for us to follow these rules? Because it was the failure of our people to follow them that caused the virus to spread so rapidly in our country. For example, we lost so many people in Banjor, Virginia, near Monrovia because people insisted on bathing bodies and in the process, rapidly and senselessly infected themselves and others, leading to many deaths. In Bong County last week, the Chief Health Administrator, Dr. Sampson Azoakoi, told our Reporter the virus had killed so many more people in Bong because they simply REFUSED to give up their cultural or religious practices, thereby spreading the virus and killing people for nothing. Dr. Azoakoi blamed this sad situation on “attitude and behavior.” Why can’t our people follow the great example of Nigeria and everybody in Nigeria, from President Goodluck Jonathan to the common person on the street? When Patrick Sawyer, the Liberian-American, knowing he had been in contact with his Ebola-infected sister, senselessly and unconscionably hopped on a plane bound for Lagos, he carried Ebola to the most populous African nation. There he infected so many people, including doctors, nurses and others, causing the death of about 42 people. Then everyone got busy—the hospital staff who, despite diplomatic pressure, refused to let Sawyer leave their premises; the Lagos State and Federal government, which immediately put other measures into place. President Jonathan went so far as to close the schools. The Federal Ministry of Health, the Nigeria Medical and Dental Association and the common people all pitched in to help. Yes, the common people of Nigeria quickly understood the deadly nature of the Ebola virus and learned that it was their PERSONAL RESPONSIBILITY to follow ALL the rules to arrest it. In the end, they lost 42 persons, but succeeded in stopping its further spread. On Monday, the World Health Organization (WHO) declared Nigeria Ebola free—the reward of the government and people’s seriousness, obedience and cooperation.We appeal to all our people, especially those in Bong County, in Banjor and all others who are inclined to stick to their cultural and religious practices to STOP SPREADING THE EBOLA VIRUS. Just as Dr. Azoakoi said, these attitudes, behaviors and practices have caused Ebola to spread in our country, and in its destructive path, to kill our people for nothing. One way to ensure that people follow the rules and take measures they need to take is for the government, national and local, at all levels, to get tough. Anyone found breaking the rules should be arrested and given a stern warning and released, but closely watched. We cannot, must not sit supinely and see people causing the deaths of others—and even themselves—and do nothing. We must take ACTION. The police and all the other security agencies should be on the alert throughout the country to make sure that people follow the rules.Everyone must learn, know and strictly observe the national slogan, popularized by LoneStar: “Ebola is real, and it kills.”Share this:Click to share on Twitter (Opens in new window)Click to share on Facebook (Opens in new window)
At the Magic Kingdom theme park in Florida, there will be the addition in early 2007 of The Laugh Floor Comedy Club, an interactive attraction based on the Pixar film “Monsters, Inc.” The “Dreams” theme will encompass the 15th Anniversary of Disneyland Paris Resort, the 25th Anniversary of Tokyo Disneyland and the continued introduction of Hong Kong Disneyland. Michael Mendenhall, executive vice president of global marketing for Disney Destinations LLC, said the campaign will permeate every step of consumers’ experience from planning their vacation to returning home. “This initiative is global in reach from a marketing perspective because of the intrinsic power of the idea. After all, everybody has a dream,” Mendenhall said. “The notion crosses all cultures, languages and geographies.” As for Leibovitz, whose iconic portraits have appeared in “Vanity Fair” and “Rolling Stone,” she will be creating a celebrity-based campaign to convey how the Disney experience touches everyone, from the famous to everyday people. “We live in difficult times and I feel, especially as a parent, that keeping dreams alive is one of the most important things you can do,” she said. “I look forward to the work ahead.” email@example.com (818)713-3758160Want local news?Sign up for the Localist and stay informed Something went wrong. Please try again.subscribeCongratulations! You’re all set! AD Quality Auto 360p 720p 1080p Top articles1/5READ MORE11 theater productions to see in Southern California this week, Dec. 27-Jan. 2Through a separate promotion called “Disney Dreams Giveaway,” 1 million “dreams” will be awarded to guests selected randomly throughout the yearlong campaign. The giveaways on both coasts include such prizes as an overnight stay inside Cinderella’s Castle at Walt Disney World Resort or the Mickey Mouse Penthouse at Disneyland Resort, traveling to each Disney resort around the world to serve as grand marshal in a Disney parade, admission to the private Club 33 restaurant, private meetings with Disney characters, and a “Golden FastPass,” which gives the winners special access to some of the most popular theme park attractions. At the Disneyland Resort in Anaheim, spring 2007 will feature the debut of Rockin’ Space Mountain, a revamped version of its popular attraction with new lighting and music and other twists. That will be followed in the summer by the debut of the Finding Nemo Submarine Voyage, inspired by the Pixar Animation Studios film “Finding Nemo.” At the Walt Disney World Resort in Orlando, Fla., an attraction called The Seas With Nemo & Friends will debut at Epcot later this year, while the live stage show “Finding Nemo: The Musical” will bow at Disney’s Animal Kingdom. BURBANK – The Walt Disney Co. on Wednesday unveiled a new yearlong global marketing campaign for its theme parks that includes the debut of some new attractions in Anaheim and Florida, features the celebrity photography of Annie Leibovitz, and offers giveaways large and small. The campaign, called “Where Dreams Come True,” replaces the successful Disneyland 50th Anniversary campaign that had encompassed all Disney theme parks and resorts around the world. “We stand on the verge of what promises to be a very exciting future,” Walt Disney Parks and Resorts Chairman Jay Rasulo said at an unveiling in New York City. “It’s about the dreams that live inside all of us.” The campaign will launch on Oct. 1 at Anaheim’s Disneyland Resort and Orlando’s Walt Disney World Resort, concluding a promotion that will include a winning family that will have the Magic Kingdom theme park to themselves with VIP treatment including entering the park on a red carpet down Main Street U.S.A.
Every current Premier League club’s best kit from the past decade 5 Hazard was in scintillating form against Cardiff New boss Sarri became just the fourth man to win his first five matches in the Premier League, as the Blues extended their 100 per cent record in style.He then revealed he told Hazard on Friday that he can boost his goal return considerably – by focusing on operating solely in the final third.“Yesterday I said to him that for me you can score 40 goals,” said Sarri of Hazard.“But you have to spend less energy far from goal and you have to play in the last 25 metres of the field. “I think that he can spend less energy than he does now at 50 to 60 metres from the opposite goal.“In these actions I think he spends a lot of energy, and he can have more energy in the last 25 metres.”Hazard’s top return for Chelsea to date is the 18 goals scored in the 2016/17 campaign, with 16 of those coming in the Premier League.But Sarri believes the 27-year-old has the chance to boost his goal return out of sight – and become the best player in Europe at the same time.“When I arrived I thought that Hazard was one of the best players in Europe,” said Sarri. Hazard completes his hat-trick 5 Warnock described Hazard as ‘unplayable’ Top nine Premier League free transfers of the decade “Now I have changed my mind: maybe he is the best. But I also think he can still improve more.”Cardiff shocked Chelsea by sneaking an early lead courtesy of Sol Bamba’s smart flicked finish from a set-piece ruse.Olivier Giroud laid on two goals in seven minutes for Hazard, though, who conjured a devastatingly clinical performance.Hazard then converted a penalty with 10 minutes to play, before Willian blasted a fine fourth for the Blues. smart causal “I thought we were in the game for 80 minutes, but again I’m really disappointed with the goals we conceded.“It’s not Chelsea’s ability. Joe (Bennett) should have won that tackle, and Bobby Reid, it’s never a free-kick.“And the penalty, I knew it was going to be a penalty 15 yards before the tackle.“I thought Willian’s too quick and Sol (Bamba) would go and tackle, not hold, especially at that stage when he was tired.“It was his only mistake though. I thought he had a good game otherwise.” impact Every time Ally McCoist lost it on air in 2019, including funny XI reactions How the Premier League table could change after the Boxing Day fixtures Willian rounded off a rampant Chelsea display LATEST FOOTBALL NEWS RANKED Sarri believes Hazard is the best in Europe Every Championship club’s best signing of the decade, including Taarabt and Dack Which teams do the best on Boxing Day in the Premier League era? MONEY 5 REVEALED Chelsea’s win moved them top of the table ahead of Liverpool on goal difference, with Jurgen Klopp’s men also winning their opening five matches.Despite Chelsea quickly finding their feet under Sarri, the former Napoli boss continues to maintain that Liverpool and Manchester City are the title favourites.Asked if he would revise that view after Chelsea’s latest win, Sarri replied: “No. I cannot change my mind from one match.“I think that in this moment Liverpool and Manchester City are in another step. But I think that we can improve.“My target is to be the best team in England, but not in one month of course. BEST OF 5 England’s most successful clubs of the past decade, according to trophies won 5 silverware Forbes list reveals how much Mayweather, Ronaldo and Messi earned this decade possible standings “Maybe one season, maybe a little more. But our target is this.“But at the moment, I repeat, for me, in my opinion, Liverpool and Manchester City are better than us.”Cardiff boss Neil Warnock heralded the “unplayable” Hazard but insisted his side ought to have cut out at least two of Chelsea’s goals.“He’s a good player, isn’t he? But that’s what you’re going to get when you play the top teams – he’s unplayable at times,” said Warnock when asked about Hazard. Maurizio Sarri has backed Eden Hazard to score 40 goals for Chelsea this season.The Belgium bagged a fine hat-trick as the Blues thumped Cardiff 4-1 at Stamford Bridge on Saturday, to move top of the Premier League on goal difference.
A chopper delivers stone to the pathways around Sliabh Liag.Mountaineering Ireland has called on Donegal County Council to halt works to put in new pathways at Sliabh Liag.The group has carried out two visits to the site and said they do not think the pathways are of a high enough standard.The group first visited the leading tourist site on August 27th and raised concerns that the contract team carrying out the works lacked relevant experience. The group then invited an internationally recognised expert in upland path management to visit the site.Dr Bob Aitken visited the site on September 16th, and although the site showed some improvement, the overall work did not meet an acceptable standard, according to Dr Aitken.A spokesman for Mountaineering Ireland said it is now again calling on Donegal County Council to stop the works.“Mountaineering Ireland again called on Donegal County Council to halt the work and to bring more relevant expertise into the project. “Despite these requests work is continuing. Slieve League is an iconic landscape which we have a shared responsibility to protect for the benefit of future generations. The quality of any remedial work at Slieve League should match the quality of this magnificent landscape.“The skills and techniques to deal effectively with upland path erosion and visitor management in sensitive environments have been developed across Britain over the last four decades. We are in the early stages of building a similar body of expertise in Ireland.“Through the Helping the Hills initiative Mountaineering Ireland has been working with a number of other organisations to share experience and learning in this area. In the meantime we shouldn’t accept a second-class solution for Slieve League or any of Ireland’s mountains.”A statement from Donegal County Council said it has noted the call by Mountaineering Ireland.“Mountaineering Ireland has raised concerns with Donegal County Council in the recent past in relation to works at Sliabh Liag and these concerns have been noted. “Donegal County Council will ensure that all works on the Sliabh Liag Project will be completed to the highest standard.”MOUNTAINEERING IRELAND CALLS ON COUNCIL TO STOP PATHWAY WORKS AT SLIABH LIAG was last modified: September 29th, 2014 by StephenShare this:Click to share on Facebook (Opens in new window)Click to share on Twitter (Opens in new window)Click to share on LinkedIn (Opens in new window)Click to share on Reddit (Opens in new window)Click to share on Pocket (Opens in new window)Click to share on Telegram (Opens in new window)Click to share on WhatsApp (Opens in new window)Click to share on Skype (Opens in new window)Click to print (Opens in new window)Tags:Mountaineering Irelandpathatssliabh liagstone
AD Quality Auto 360p 720p 1080p Top articles1/5READ MOREWalnut’s Malik Khouzam voted Southern California Boys Athlete of the Week THURSDAY: A food fair to raise money for local firefighters who battled the Topanga Fire will be held from 11 a.m. to 2:30 p.m. on Oxnard Street in front of the Westfield Promenade Mall. Local restaurants will donate dishes. The Burbank African Violet Society will meet at 7 p.m. at Magnolia Park United Methodist Church, 2828 W. Magnolia Blvd., Burbank. A business mixer hosted by the Calabasas Chamber of Commerce and the Eden Surgical Wellness Center will take place from 5:30 p.m. to 7 p.m. at the wellness center, 23951 Craftsman Road, Calabasas. Mail Datebook entries – including time, date, location and a phone number – to Daily News City Desk, P.O. Box 4200, Woodland Hills, CA 91365; fax (818) 713-0058; e-mail firstname.lastname@example.org. 160Want local news?Sign up for the Localist and stay informed Something went wrong. Please try again.subscribeCongratulations! You’re all set!
AD Quality Auto 360p 720p 1080p Top articles1/5READ MORERose Parade grand marshal Rita Moreno talks New Year’s Day outfit and ‘West Side Story’ remake In Sacramento, 2005 was a year of ugly power politics, of bitter partisanship and special-interest recalcitrance. State leaders refused to work together to confront the looming crises in pensions and infrastructure, to fix the state’s gerrymandered redistricting system, or confront the systemic problems in public education. Instead of cooperation, we got political war, culminating in an ultimately fruitless special election, in which disgusted voters turned down everything and told the politicians to start doing their jobs. Nonetheless, there were still bright spots. California’s economy continued to rebound, and swelling state revenues wiped out an anticipated budget deficit. But politically, the state of the state is worse today than it was a year ago. Over the past year, most of California’s pressing problems have only grown worse. Meanwhile, Schwarzenegger, once the leading advocate for change, has been greatly diminished, and now labors to restore his credibility in an election year, when the vitriol and partisanship are only likely to increase. But if California’s “year of reform” came to a crashing halt in mid-2005, that’s when Los Angeles’ began in earnest. Fed up with James Hahn’s corrupt brand of politics, his kowtowing to special interests and his utter lack of vision, L.A. voters triumphantly elected Antonio Villaraigosa as mayor in May. With an amazing level of energy and dedication, Villaraigosa then stormed the city, visiting every neighborhood, and securing critical support for the battles that loom ahead. And those battles will be many. Villaraigosa has vowed to stop Hahn’s proposed expansion of Los Angeles International Airport, to end the practice of dumping trash in Sunshine Canyon and to rein in public-employee unions. Just in case that weren’t enough, he’s also committed himself to the most daunting undertaking of all – reforming the Los Angeles Unified School District. At the end of 2005, the prospects for Los Angeles are brighter than they have been in a long, long while. Over the past 12 months, we have witnessed real progress. The long-awaited Orange Line busway in the San Fernando Valley has been an overwhelming success, and the Valley economy is the envy of the region. Even in the sports world, we have seen the continued dominance of USC football, the Angels made the playoffs again and there are encouraging signs that the Dodgers are coming back to life. Of course, L.A. still has its problems, but 2005 was very much a year of reform, or at least a year that carried the promise of reform in the future. Even much of the bad news from Sacramento contained seeds of hope – hope for a housecleaning in the 2006 elections, and hope that Villaraigosa will be a more effective reformer, having learned from Schwarzenegger’s missteps. For all its disappointments, 2005 also included plenty of joys that give us plenty to look forward to in 2006.160Want local news?Sign up for the Localist and stay informed Something went wrong. Please try again.subscribeCongratulations! You’re all set! Remember “The Year of Reform?” That’s what Gov. Arnold Schwarzenegger called 2005 last January, back when his public-approval ratings were even bigger than his biceps, and when Sacramento Democrats still cowered in his presence. But the promise didn’t live up to the hype, at least not in Sacramento. In L.A., on the other hand, it was a different story.
This week Donegal Daily’s fitness columnist Emmet Rushe, owner and operator of Rushe Fitness, talks of how we should channel our energy into looking after ourselves as opposed to venting to no real effect on social media following the announcement of Trump’s imminent presidency.This week saw one of the biggest upsets the U.S presidential elections has seen in recent years.Donald Trump was elected as the 45 th President of the USA. He is the only president elected, having no former Military or political experience.The internet exploded on Wednesday when it was announced.People around the world were expressing their utter disapproval at the thought of Trump as the most powerful man in the world.There were cries of shame, pity, anger, disbelief, contempt and every other synonym that you could think of when the news was announced. People were full of passion and were letting the world know through the power of social media.Great! Super! Well done!Have you finished venting now? Because it means nothing. Donald Trump is the President of the USA, not Ireland.If you can be so passionate about a subject matter that will have little to know effect on you, let’s see if we can muster up some of that passion and put it to better use.Every day, I see and hear people say that they just can’t find the time, motivation, energy to train or eat better. Every day, I see people who give up on their goals, because they just don’t have the drive to proceed or, sometimes, even to start.Yet, Donald Trump is President Elect of the USA, and these same people, can spend all day on Facebook, voicing their opinion and getting into arguments.They could stay up all night and watch the live feed as it gave the results as they happened, and yet they would claim that they are too tired when they get home to prepare a proper meal or to go and exercise.Where is the passion when it comes to ourselves? Where is the passion when it comes to our health? Where is the passion when it comes to the rising obesity epidemic? The rise in diabetes? The rise in obesity related diseases? Whenever these things come up, there is silence.Yes, there will be an increase in our health once January hits, but let’s face it, realistically it will be short lived.The issue during the week wasn’t the fact that Trump was elected, it was the fact that the apple cart had been over turned.We have become very good at acceptance.We accept that we are in an obesity epidemic.We accept that our obesity is making us a more unhealthy and unwell nation.We accept that Type 2 diabetes is now commonplace.We accept that heart disease is part of growing old.But they aren’t. We are doing it to ourselves.So, let’s tip the apple cart a little bit more and break from the norm.Yes, it will make you uncomfortable.Yes, it will be difficult at times.Yes, you will face people with different opinions to you.But what can achieve, when we finally take control of our health and wellbeing, will be worth it. We need to start using the passion we have for things out of our control and use that passion to make ourselves a healthier, fitter, better version of ourselves.God Bless America, I mean Ireland.#TrainSmartYou can find out more information visit my website or contact me on FacebookDD Fitness: How Trump can help you lose weight was last modified: November 12th, 2016 by Emmet RusheShare this:Click to share on Facebook (Opens in new window)Click to share on Twitter (Opens in new window)Click to share on LinkedIn (Opens in new window)Click to share on Reddit (Opens in new window)Click to share on Pocket (Opens in new window)Click to share on Telegram (Opens in new window)Click to share on WhatsApp (Opens in new window)Click to share on Skype (Opens in new window)Click to print (Opens in new window)
Eddie Hearn believes George Groves will defy many predictions and take the fight to Carl Froch in Saturday’s world title showdown.Groves has been widely tipped to box on the back foot rather than engage with the rugged champion, having used similar tactics to beat arch-rival and fellow West Londoner James DeGale in 2011.But Hearn, who promotes both Froch and Groves, thinks the challenger may well adopt a different gameplan in the biggest fight of his life.“I don’t think he’s going to run at all. I think he’s going to stand there, plant his feet and try to push Carl back,” Hearn told West London Sport.Groves is convinced he will overcome Froch.“I don’t think he’s going to go on the back foot. Most people do, so I may be wrong. I’ve just got a feeling that he’s not going to do that.“He’s got to use his movement and speed, but if you fight on the back foot against Carl Froch – this man’s a nightmare – he will hunt you down as he’s relentless.“If you start that way then three or four rounds in you’re going to be thinking ‘he won’t leave me alone’ and I don’t think George will feel he’s better off doing that.“No, I think George will want to show Carl that he’s in a fight. But I could be wrong – it’s just fascinating to see how it’s going to unravel.“It’s a huge fight. We’re attracting really big numbers for pay-per-view and the public are really getting behind the fight and are fascinated by it.“People are fascinated by all the talk and the mystery of what will happen. Obviously Carl is the favourite, but George is one of the biggest young stars in the sport.“I’m fascinated to see how it’s going to turn out, because I really have no idea. People talk about what sort of fight it’ll be but until that bell goes we just don’t know.”Froch, 36, holds the IBF and WBA super-middleweight titles and is the strong favourite, having lost only twice in a 33-fight career and consistently operated at the top level.He avenged one of those defeats by beating Mikkel Kessler earlier this year and a victory in Manchester would keep him in the frame for a rematch with American star Andre Ward, who outclassed him when they met in 2011.Groves is unbeaten in his 19 professional fights and has held the British as well as Commonwealth title.This weekend’s bout represents a significant step up in class for the 25-year-old, who is looking to make a name for himself in an exciting weight division which has previously starred the likes of Nigel Benn, Chris Eubank and Joe Calzaghe.Groves has been trained by Paddy Fitzpatrick.And Hearn said: “I liken this fight to Chris Eubank against Nigel Benn.“The fact is that when Eubank fought Benn his record was 24-0 and his best win was against Kid Milo or Anthony Logan.“Well, George has beaten James DeGale, who is on another level to fighters like that. We all know the result when Eubank fought Benn.“Is it too early for George? We’ll find out on Saturday. Until you actually take that chance you just don’t know.“You’ve got to look at what Froch has achieved, but George is a very live challenger in this fight.“You get some fights where you just can’t see a way the challenger can win, but a lot of people are choosing Groves.“The fascination is over whether George is ready to mix at that level. One thing you can’t deny is that he’s never mixed at that level before, but is he good enough to?“It may be that he’s more than ready. It may be that he wins and becomes champion, but he may not be. It’s that fascination that makes people interested.“And in George’s head, he can’t lose this fight. That’s the worrying thing for Froch, who has much more to lose.“That might work to his [Groves’] advantage or disadvantage, I don’t know. All these questions are what makes it so fascinating.”See also:Relaxed Groves unfazed by Froch – trainerConfident Groves squares up to Froch after final press conferenceGroves: Froch is wrong, I’m ready for himFroch claims Groves will be ‘annihilated’Groves stays cool at tense weigh-inGroves reveals his plan to beat Froch in Saturday’s world title clashFroch v Groves: Live updatesGroves says Froch ‘has 48 hours to readjust’ after gameplan is revealedPromoter predicts Froch-Groves 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 Follow West London Sport on TwitterFind us on Facebook
Did you know your heart is an electrical appliance? That’s right. Currents of electrical ions are vital to its function as a contractile organ. Now, researchers at the University of California have found another thing electricity does for your heart: it guides the developing heart into the proper shape. This is a key study showing how epigenetic factors – factors above and beyond the genetic code – are essential for the formation of body parts. The research team, publishing in PNAS,1 explained the purpose of their investigation (Note: morphogenesis refers to the origin of shape, and cardiomyocytes are the specialized muscle cells that make the heart beat): Cardiac morphogenesis is a complex process that is mediated by a coordinated set of cellular and molecular as well as environmental factors. Recent studies have shown that epigenetic forces such as cardiomyocyte contractility and intracardiac hemodynamic flow regulate this process. Furthermore, in vitro studies suggest that cardiomyocytes can realign themselves according to electrical conduction directionality. However, because electrical cardiac conduction and mechanical contractile forces are intimately coupled in the intact heart, it is difficult to assess the individual contribution of these influences to overall heart organogenesis. Here, we make use of several zebrafish cardiac mutants to uncouple these two influences, and find that electrical conduction exclusive of contractile influences can directly participate in remodeling and morphogenesis of the vertebrate heart.In other words, electrical conduction guides the individual heart cells into position during heart development and repair. They said in the Discussion part of their paper that it is known that “The direction of growth and orientation of various cell types in tissue culture can be influenced by externally applied electric fields.” They added, “Furthermore, endogenous [inside organism] electric currents exist in a variety of tissues and have been hypothesized to influence cell migration and shape.” This paper announces confirmation of that hypothesis for heart formation: “Our in vivo results [using living zebrafish] indicate that physiologic electric currents can indeed have an impact on cell morphology and overall cardiac organogenesis.” The mutant fish without the electrical conduction working properly developed heart disease. So how does this work? They explained, “These electrical effects might be mediated through intracellular calcium fluxes which can affect cell polarization. Furthermore, a number of cell surface receptors… can also be redistributed in the cell membrane by electric fields.” Does this finding provide hope for heart patients? Patients with electrical conduction disorders get better when the beats are re-synchronized. The researchers explained why that works: “Thus, overall cardiac improvement from the resynchronization of the ventricles in heart failure patients manifesting conduction disorders may be due to beneficial realignment and improved remodeling of the myocardium primarily from proper and synchronized electrical signaling.” Get the electricity right, and the heart shapes up. Now those defibrillation devices and electrical heart stimulators start to make more sense. This means that stem cell therapy (07/20/2010) may need an electrical jumpstart to work properly: “Given that previous cardiac cell-based therapy has provided only a modest improvement in cardiac function,” they ended, pointing therapy in a new direction, “electrical cell?cell communication and stimulation may be required for optimal integration and alignment of engrafted embryonic cardiomyocytes and skeletal myoblasts in the injured myocardium to improve overall myocardial performance.” Live better electrically!1. Chi, Bussen et al, “Cardiac conduction is required to preserve cardiac chamber morphology,” Proceedings of the National Academy of Sciences, published online July 30, 2010, doi: 10.1073/pnas.0909432107.This fascinating discovery is but the tip of an iceberg that will guide biology into the future: epigenetics. We have learned much about genetics – the DNA code that provides the information for building proteins and the cell’s building blocks. But genetics does no more than deliver the bricks, pipes and wire to the construction site and drop off a blueprint. What directs the parts into their correct position at the correct time? What makes some genes get expressed in cardiac cells, and other genes get expressed in nerve cells? If all the cells have the same blueprint, why do they become so different in different parts of the body? Clearly much more is going on than providing each cell with a blueprint. Here we see one example of an epigenetic factor, where electrical currents are involved. Imagine how precise these currents must be positioned to guide cells into the shape of an auricle or ventricle, to say nothing of guiding all the ancillary nerve cells and blood vessels into place. What switches on the electrical currents, and orients them properly? Do you get a brief glimpse of mind-boggling complexity going on inside the womb as a baby’s heart forms and begins beating in just 9 or 10 weeks from the time the baby began as a single cell? The complexity of development was presented briefly in the second half of the recent film Darwin’s Dilemma from Illustra Media. Scientists like Richard Sternberg and Jonathan Wells commented that the complexity of development and epigenetic factors is so vast, so poorly understood, so impermeable to an origin by chance, it leaves regular genetics far behind. Did the PNAS scientists need to ask Darwin for help? Ha! They needed him like a hole in the heart. They never mentioned evolution once in their paper. Odd, isn’t it, when the Darwiniacs assure us that nothing in biology makes sense except in the light of evolution. Science is only beginning to ask the questions about how factors beyond genetics guide molecules into specialized cells, then tissues, then organs, then a complete organism (the computer graphics in Darwin’s Dilemma are excellent for illustrating this). Morphogenesis cannot be described in a one-dimensional code. There are hierarchies of codes involved in the development of each cell and organism. If Darwin could not survive a genetic code arising by chance (see online book), how on earth will he survive hierarchies of codes? In the condition his theory was already in, it’s enough to cause a massive coronary. You have a designed heart; so have a heart for design, because the future looks healthy for intelligent design science.(Visited 32 times, 1 visits today)FacebookTwitterPinterestSave分享0
Astronomers display creativity at rationalizing their inability to find what they believe makes up the bulk of the universe.Something is wrong with a theory that can’t find 95% of the universe. Cosmologists can’t find dark matter or dark energy, but their theories need it. They can’t explain the motions of galaxies and star clusters without it, they can’t explain cosmic acceleration without it, and they can’t explain the big bang without it. It’s gotta be there! Where is it? What is it? To hide their embarrassment, they resort to imagination and storytelling.Giant atoms could help unveil ‘dark matter’ and other cosmic secrets (The Conversation). A PhD student at the University of Leeds introduces the problem. “The universe is an astonishingly secretive place,” Diego A. Quiñones begins. “Mysterious substances known as dark matter and dark energy account for some 95% of it. Despite huge effort [sic] to find out what they are, we simply don’t know.” He postulates a new probe for the elusive stuff using atoms stretched 4,000 times their original size, taut as a guitar string that could vibrate with the slightest pressure, such as whatever-dark-matter-is might produce.The case for co-decaying dark matter (Phys.org). Maybe as the universe cooled as it expanded all that dark matter was “annihilated away.” That’s the creative solution in this article. In fact, maybe it annihilated faster than cosmologists thought it did. If so, it would be a waste of time to look for it directly. Indirect methods might work better. Is that something like daydreaming about it?No trace of dark matter in gamma-ray background (University of Amsterdam). Another search method has come up empty. It’s beginning to sound like a broken record; we came, we saw, we were conquered by non-detection.Researchers from the University of Amsterdam’s (UvA) GRAPPA Center of Excellence have just published the most precise analysis of the fluctuations in the gamma-ray background to date. By making use of more than six years of data gathered by the Fermi Large Area Telescope, the researchers found two different source classes contributing to the gamma-ray background. No traces of a contribution of dark matter particles were found in the analysis….To date, the Fermi telescope has not detected any conclusive indication of gamma-ray emission originating from dark-matter particles. Also, this latest study showed no indication of a signal associated with dark matter. Using their data, [Mattia] Fornasa and colleagues were even able to rule out some models of dark matter that would have produced a detectable signal.‘Our measurement complements other search campaigns that used gamma rays to look for dark matter and it confirms that there is little room left for dark matter induced gamma-ray emission in the isotropic gamma-ray background’, says Fornasa.**That fail is for NASA.Universe May Have Lost ‘Unstable’ Dark Matter (Live Science). Reporter Jesse Emspak turns to a theory by Russians for light in the dark. But can they really claim this? “We have now, for the first time, been able to calculate how much dark matter could have been lost and what the corresponding size of the unstable component would be.” If you don’t know what you are starting with, and can’t see it, how can you calculate anything about it? They add to the folly, saying, “dark matter may still be disintegrating even now.” None of this helps anyway. Their calculations can only account for a loss of 5% of dark matter since the big bang.First test of rival to Einstein’s gravity kills off dark matter (New Scientist). Another way to cover up embarrassment is to distract attention to a rival theory. “A controversial approach to gravity that challenges Albert Einstein and suggests dark matter doesn’t exist has passed its first test,” reports Mark Anderson. “Modified Newtonian Dynamics” (MOND) claims that gravity acts differently at different scales. Toss in some quantum mechanics, relativity, information theory and string theory, like Erik Verlinde does at the University of Amsterdam does, and you don’t need dark matter. Majority cosmologists will likely find this solution worse than the disease. “So if Verlinde’s is the better match, what’s the problem?” Anderson writes. Answer: “Gravitational heresy.” It “borders on sacrilege” to propose modifying some of the best-tested theories in physics, one critic says.More Dark MysteriesPhys.org announced a cosmic puzzle, “The mystery of part-time pulsars.” This isn’t about dark matter per se, but it relates to another puzzle lurking “in the dark regions of space.” Suraiya Farukhi says, “A new discovery has upended the widely held view that all pulsars are orderly ticking clocks of the universe.” The famous Arecibo radio telescope caught two “extremely strange” pulsars doing a “cosmic vanishing act” – “Sometimes they are there, and then for very long periods of time, they are not.” These mysterious spinning stars somehow switch their radio beams on and off. “They’re ON and then they’re gone, disappearing without any apparent warning.” Maybe these are just oddballs. No; “The most important implication of this discovery is that there must exist an extremely large number these vanishing act pulsars.” In fact, they could “far outnumber normal pulsars.” The abnormal is set to become the new normal.Another cosmic puzzle was announced by Nature. Remember the lavish celebrations when the LIGO instrument appeared to confirm Einstein’s theory last year by detecting gravitational waves? Get this: “LIGO black hole echoes hint at general-relativity breakdown.” The article says, “Researchers find echoes in the LIGO data that show tentative signs of firewalls or other exotic physics.” Apparently the law fails at the edge of black holes, but more analysis will be required to be sure. “The echoes could yet disappear with more data. If they persist, the finding would be extraordinary.” In support of relativity, though, a report on Space.com suggests that Einstein’s equations explain how the sun was able to shed some of its angular momentum by releasing it through hot photons emitted from the surface. The low angular momentum in the sun, where it should be the highest according to the Law of Conservation of Angular Momentum, has been a long-standing problem. The effect is slight, but the sun has been shedding it a long time, the article says. What this will do to theories of stellar evolution is not yet known.And you thought Science had escaped the occult into the Age of Reason. It has evolved into Reasons for the Occult. (Visited 173 times, 1 visits today)FacebookTwitterPinterestSave分享0