Digby Ioanes try celebration has raised the bar pretty his as far as celebrations go. But Blues wing Rene Ranger thought he’d give it a go – with some help from his friends… LATEST RUGBY WORLD MAGAZINE SUBSCRIPTION DEALS
Lead Architect: ShareFacebookTwitterPinterestWhatsappMailOrhttps://www.archdaily.com/929104/two-houses-by-the-lake-gaudenzi-arquitetura Clipboard CopyAbout this officeGaudenzi ArquiteturaOfficeFollowProductSteel#TagsProjectsBuilt ProjectsSelected ProjectsResidential ArchitectureHousesPetrópolisBrazilPublished on November 27, 2019Cite: “Two Houses by the Lake / Gaudenzi Arquitetura” [Duas casas no lago / Gaudenzi Arquitetura] 27 Nov 2019. ArchDaily. Accessed 10 Jun 2021.
SHARE Emerald Ash Borer Puts Trees on Path to Functional Extinction Home Indiana Agriculture News Emerald Ash Borer Puts Trees on Path to Functional Extinction Facebook Twitter Facebook Twitter Previous articlePrepare for Big Crops that Leave Fields in Need of Nutrients on the HAT Tuesday PodcastNext articleLame-Duck Session Brings Hope of More COVID Relief for Agriculture Purdue University News Service SHARE Ash trees, like the one seen here, are weakened as emerald ash borer larvae feed under their bark. The invasive pests eventually kill the trees and have been spreading throughout the United States for nearly two decades. Purdue’s Songlin Fei has shown that ash trees are not regenerating well in forests where the ash borers have invaded, leaving the tree species likely to become functionally extinct. (Photo provided by Songlin Fei)Since the emerald ash borer’s introduction to the United States at the beginning of the 21st century, forest ecologists and government officials have striven to stem its destruction of ash forests. Despite those efforts, the invasive pest may be winning the war.Mining 16 years of U.S. Forestry Service Forest Inventory Analysis data for 960 counties, Purdue University professor Songlin Fei has shown that in impacted areas, young trees are dying before they can reach their reproductive stages. Unable to compete with larger trees or resist the emerald ash borer, American ash trees may be doomed to functional extinction.“As we see overstory ash trees dying in these forests, we had hoped that ash would respond to the emerald ash borer like many forests do to fire, regenerating after the fire is gone,” said Fei, a professor of forestry and natural resources and Purdue Agriculture’s Dean’s Chair of Remote Sensing. “What we found is that these ash trees are not surviving. There is more mortality in the small-diameter ash trees than there is recruitment, and few are maturing into large-diameter trees capable of producing seed. In the long run, we will run out of material and no longer have ash reaching the reproductive age.”Emerald ash borer, a beetle native to northeast Asia, was first detected in Michigan in 2002. Its western range has reached South Dakota in the north down to Texas in the south. It’s in every state east of that line except for Mississippi and Florida. Its larvae burrow under ash tree bark to feed, eventually weakening and killing trees, with losses estimated in the tens of millions so far.Fei and colleagues from the U.S. Department of Agriculture Forest Service examined records from the U.S. Department of Agriculture’s Animal and Plant Health Inspection Service (APHIS) to catalog the locations of emerald ash borer infestations from three periods: 2002–06, 2007–12, and 2013–18. They paired that with the Forest Inventory Analysis data on tree populations collected from 2002-2007 and 2013-2018 to see how the invasions affected ash trees at different points after the ash borer first appeared in an area.They discovered that in the years near emerald ash borer’s introduction, ash seedling populations were abundant in the forests but started to thin out without growing to maturity. In later years, the density of young trees declined significantly. Later periods had 500 fewer seedlings per hectare and sapling recruitment was 50% lower than the tree mortality rate.“Despite this widespread regeneration, ash trees in the smallest overstory class died at faster rates than they were recruited from seedlings or saplings, resulting in negative population trajectories on plots that have been invaded for more than 10 years,” according to the authors’ findings, which will be published in the January issue of Forest Ecology and Management. “This trend suggests that ash will continue to decline in abundance and may become functionally extinct across the invaded range of emerald ash borer.”Fei cautioned that the results do not suggest that ash trees will disappear altogether from the U.S. However, being functionally extinct means that they will not provide economic value as hardwoods or the ecological services they long have in forested areas.“Like elm, which was decimated by the Dutch elm disease, there may be places with ash trees and seedlings in the understory, but they won’t mature in populations large enough to fulfill their traditional economic or ecological purposes,” Fei said. “There also are peripheral areas that haven’t been invaded by the emerald ash borer yet. In those places, we still have a chance and we do want to fight there to keep those forests safe.”Ash trees in residential areas can be treated with insecticides to keep emerald ash borers away. People are also encouraged to buy firewood locally and not to move it long distances that could help the pest expand its range. More information is available here.A National Science Foundation Macrosystems Biology grant, the USDA McIntire-Stennis program and the USDA Forest Service funded Fei’s work. By Purdue University News Service – Nov 10, 2020
Previous articleFleming buzzer beater lifts Charleston Southern to OT winNext articleJarrett carries Jackson State over Grambling State 63-59 Digital AIM Web Support Twitter By Digital AIM Web Support – April 6, 2021 Facebook TAGS Twitter WhatsApp LONDON & GALWAY, Ireland & SAN DIEGO–(BUSINESS WIRE)–Feb 22, 2021– Cell therapy company ONK Therapeutics and blood cancer charity Anthony Nolan have entered into a collaboration to facilitate the development of the next-generation natural killer (NK) cell therapies to improve the lives of patients with hematological malignancies and solid tumors. Anthony Nolan Cell & Gene Therapy Services will provide a consistent supply of umbilical cord blood and cord-derived NK cells as a choice of starting material for both ONK Therapeutics’ research activities and continued process development work. This source material is scalable and ethically-sourced from consenting donors. The parties bring together their extensive experience in cell sourcing, cell processing, translational research, understanding of the tumor microenvironment, and exploration of NK cells as a foundation for cellular immunotherapy. In doing so they aim to expedite the development of much-needed new lifesaving cell therapies for patients with a broad range of cancers. Diana Hernandez, Head of Immunotherapy at the Anthony Nolan Research Institute says: “Our innovative partnership with ONK Therapeutics will serve to accelerate vital research and development into hematological and solid cancer treatments. We see this as an exciting opportunity which will ultimately lead to better treatments, improving the lives of many more cancer patients.” Chris Nowers, CEO of ONK Therapeutics says: “Anthony Nolan has a rich heritage in stem cell therapy research, including an enviable understanding of the biology of NK Cells and their processing. We look forward to continuing to partner with their team and to benefiting from their extensive know-how as we drive our programs towards clinical trials and beyond.” -Ends- Anthony Nolan Cell and Gene Therapy Services –www.anthonynolan.org/clinicians-and-researchers/cell-and-gene-therapy-services Anthony Nolan is the pioneering charity that saves the lives of people with blood cancer and blood disorders who need a stem cell transplant. Anthony Nolan’s Cell and Gene Therapy Services aim to facilitate ethical research and development through the sourcing and supply of donor starting materials to researchers and developers. With a register of over 850,000 donors, a cord blood bank, and four decades of experience providing stem cells, Anthony Nolan has the infrastructure, the expertise, and the skills to support the needs of the cell and gene therapy industry. LinkedIn: www.linkedin.com/showcase/anthony-nolan-cell-&-gene-therapy-services/ Contact: [email protected] ONK Therapeutics –www.onktherapeutics.com ONK Therapeutics Ltd is an innovative cell therapy company dedicated to developing the next generation of ‘off-the-shelf’, dual-targeted NK cell therapies targeting hematological malignancies and solid tumors. The company was founded in 2015, by Prof. O’Dwyer MD, of NUI Galway, an expert in translational multiple myeloma research, the tumor microenvironment, and exploitation of NK cells as cellular immunotherapy. Its core proprietary off-the-shelf platform is based on a dual-targeted NK cell expressing both a chimeric antigen receptor (CAR) targeting a known tumor antigen and a TNF-related apoptosis-inducing ligand variant (TRAILv) targeting the death receptor pathway (i.e. DR4 or DR5). This unique approach has the potential to enhance efficacy by addressing both intrinsic (e.g. CAR engagement of a tumor-specific antigen) and extrinsic (e.g. signaling through the death receptor pathway) apoptotic pathways and to reduce the susceptibility to possible target antigen escape through the engagement of tumor antigen-independent TRAILv. Its pre-clinical pipeline comprises four programs:The lead program, ONKT101, is a dual-targeted NK cell therapy incorporating a CD19 CAR and TRAILv targeting DR5, intended for the treatment of relapsed/refractory B cell malignancies. This program is partnered with Avectas, with the company having responsibility for development to Phase 1ONKT102 combines an optimized affinity CD38 CAR and a TRAILv targeting DR5, intended for the treatment of patients with relapsed/refractory multiple myelomaONKT103 combines a TA-MUC1 CAR with a TRAILv targeting DR5, for the treatment of solid tumorsONKT104 combines a CLL-1 CAR with a TRAILv targeting DR4, for the treatment of AML In addition to the unique off-the-shelf, dual-targeted NK cell therapy platform, the company has a strong research focus on strategies to enhance homing and persistence, and overcome exhaustion, including the exploration of proprietary gene edits, such as the deletion of checkpoint inhibitory receptors in NK cells. ONK Therapeutics is headquartered in the med-tech hub of Galway, Ireland, with a wholly-owned US subsidiary, ONK Therapeutics, Inc. based at JLabs @ San Diego. Shareholders include Acorn Bioventures, ALSHC (principally Seamus Mulligan), and Enterprise Ireland. Follow us on Twitter and LinkedIn. LinkedIn: www.linkedin.com/company/onk-therapeutics Twitter: ONK Therapeutics (@OnkTherapeutics) / Twitter NOTES TO EDITORS About Anthony Nolan Anthony Nolan saves the lives of people with blood cancer. The charity uses its register to match potential stem cell donors to blood cancer and blood disorder patients in need of stem cell transplants. It also carries out pioneering research to increase stem cell transplant success and supports patients through their transplant journeys. Every day Anthony Nolan gives three people a second chance at life. Find out more at www.anthonynolan.org Note to sub-editors Please note that Anthony Nolan changed its name in 2001 and is no longer known as Anthony Nolan Trust. What is a stem cell transplant? If a patient has a condition that affects their bone marrow or blood, then a stem cell transplant may be their best chance of survival. Doctors will give new, healthy stem cells to the patient via their bloodstream, where they begin to grow and create healthy red blood cells, white blood cells, and platelets. Key statisticsAbout 2,000 people in the UK need a stem cell transplant from a donor every year90% of donors donate through PBSC (peripheral blood stem cell collection). This is a simple, outpatient procedure similar to giving bloodWe need more young men to sign up, as they are most likely to be chosen to donate but make up just 18% of the registerWe need more people from Black, Asian, and minority ethnic (BAME) backgrounds to sign up. Only 70% of transplant recipients receive the best match. This drops dramatically to around 37% if you’re from a Black, Asian, or ethnic minority background.Blood cancer is the fifth most common type of cancer in the UK and the third biggest cancer killer. It accounts for 9% of all new cases of cancer diagnosed in the UK.It costs £40 to add each new donor to the register so we always need financial supportTo join the Anthony Nolan register, you must be 16-30 and healthy. Anthony Nolan’s world-leading Research Institute has shown younger donors offer better survival rates for patients. Facebook View source version on businesswire.com:https://www.businesswire.com/news/home/20210222005052/en/ CONTACT: Media enquiries (for ONK Therapeutics) International Sue Charles, Charles Consultants – +44 7968 [email protected] Ireland Ray Gordon, Gordon MRM – +353 87 [email protected] Media enquiries (for Anthony Nolan) For more information about the charity, please call the Anthony Nolan press office on 0207 424 1300 or [email protected] For urgent out-of-hours media enquiries, call 07881 265 285. KEYWORD: NORTH AMERICA UNITED STATES IRELAND UNITED KINGDOM EUROPE CALIFORNIA INDUSTRY KEYWORD: ONCOLOGY HEALTH STEM CELLS GENETICS CLINICAL TRIALS BIOTECHNOLOGY SOURCE: ONK Therapeutics Copyright Business Wire 2021. PUB: 02/22/2021 03:00 AM/DISC: 02/22/2021 03:01 AM http://www.businesswire.com/news/home/20210222005052/en Pinterest Pinterest Anthony Nolan Cell & Gene Therapy Services and ONK Therapeutics Announce Collaboration Local NewsBusiness WhatsApp
1983 receptions of subionospheric signals radiated from Siple, Antarctica (L = 4.3) to neighboring stations Palmer (L = 2.3), Halley (L = 4.3), and South Pole (Λ = 74°), each ~ 1500 km from the horizontal (magnetically east-west) VLF transmitting antenna at Siple, were found to be strongly dependent upon azimuth and upon signal frequency. At Palmer, located equatorward in the broadside direction with respect to the antenna, signals near 2.5 kHz were often well defined, while the third harmonic of the transmitted signal, near 7.5 kHz, was not detected. Meanwhile, at Halley, the third harmonic was regularly observed and directionally stable, while the fundamental was often weak or undetectable. The field strength of the third harmonic component at Halley exceeded by ~ 40dB the level of the fundamental, when both were normalized to the same antenna input power. The large size of these effects is attributed in part to antenna properties that favor the endfire direction (toward Halley) at the 3d harmonic of the antenna half wave resonance frequency, and in general provide greater efficiency at higher frequencies. Other factors are high waveguide attenuation in the 2–4 kHz range and azimuth dependent differences in the propagating modes. The observed effects represent a way of extending the effective frequency range of the narrowband Siple antenna system, and also, by using the new crossed dipole configuration at Siple, of selectively probing certain regions of the Earth-ionosphere waveguide.
THE REAL SBOA AUDITS FINDINGS IS IN THE “SUPPLEMENTAL COMPLIANCE REPORT”Last Friday, the news we have been waiting for finally broke. The results of the 2014 State Board of Accounts Audit of the City of Evansville’s books were made public. The City County Observer finds no joy in having been right about what those results would be, but we are proud that we told our readers the pure, unvarnished truth about the state of Evansville’s finances.We are proud to have stood up for the truth offered to us by former 5th Ward Councilman John Friend, CPA, former 3rd Ward Councilwoman Stephanie Brinkerhoff-Riley, and Mayoral Candidate, State Rep. Gail Riecken. We gave these conscientious public servants the respect they deserve for doing due diligence in their positions while the Mayor and his political appointees discredit them in a very personal and mean-spirited manner. We will always be proud of offering them a non bias platform to speak the truth from.We hope that all of our readers take the time to read the SBOA findings on the state of City of Evansville finances as of the end of 2014, which can be accessed through links we posted on Friday, February 26. It is clearly stated that the SBOA made an “adverse” finding, but we are already reading the Mayor and his chief “spin masters’” versions of the findings in the Courier and Press. It appears the local main stream media has again fallen into line with the “propaganda machine” of the Winnecke Administration.Two quotations about the outcome of the audit appear to be red flags waving in the breeze for all to see if only they open their eyes. The first is a part of the audit findings by SBOA: “The cash balance of any fund may not be reduced below zero. Routinely overdrawn funds could be an indicator of serious financial problems which should be investigated by the governmental unit.” It is no secret that our accounts are routinely overdrawn, but City Controller Russ Lloyd’s response is rather alarming. Lloyd’s response: “The city is aware that certain cash balances in particular funds may fall below zero on a given day. This is due to sporadic revenue streams and constant disbursement requests. Is is the city’s established policy that each department director and correlated fund manage their budget throughout the year to ensure all funds begin and end the year with a positive cash balance.”We are not CPAs, but we are reasonably certain that the layman’s translation of that statement is “We do all we can to juggle the books so they appear balanced on the first and last days of the year.”City Controller Russ Lloyd, Jr in his “Plan of Correction” (which would not be necessary in an acceptable audit) makes mention of ways to lessen the City’s financial shortfalls. He suggests that payroll can be lessened by a hiring freeze and reduction in the number of employees through attrition and job reclassification. Those are the exact solutions that SBR, John Friend, and Gail Reicken warned voters about, but they were dismissed by Mayor Winnecke, Controller Russ Lloyd Jr as something that was absolutely not in their plans for our “vibrant city.”We also take note that there is no discussion of cutting back on the expenses involved in the planned dog park and bike trails, but there is talk of cutting the number of employees who deliver city services. We are especially concerned that there could be a reduction in the number of public safety employees. Only last week, the City Council meeting had a number of Jacobsville residents speak about the high crime rate and the widespread blight in their neighborhood. It’s reasonable to wonder if they would have supported the North Main renovations, if they had been aware that our finances are dicey enough that we could be facing a possible reduction in the number of firefighters and policemen.It becomes evermore clear to us, and to other reasonable minds, that Evansville is being lead by a less than truthful City Controller who was also was a failed Mayor. We can only hope he don’t guide Evansville down the path to failure similar to Detroit. It is time for the people of this city to unite in a movement to demand transparency and accountability from both our officials and the local main stream media.Oh, the SBOA SUPPLEMENTAL COMPLIANCE report for the CITY OF EVANSVILLE dated January 1, 2014 to December 31, 2014 concerning the Overdrawn Cash Balances for the General Fund shows a balance of $307,140 as of December 31, 2014, the fund would have shown a deficit balance of $5,888,660 as of December 31, 2014, if not for the following items:1. The Wastewater Utility prepaid the 2015 payment in lieu of taxes payment totaling$2,428,0002. The City did not pay the General fund’s portion of hospitalization bills for the 3rd quarter of2014 totaling $3,767,800.FOOTNOTE: Our next “IS IT TRUE” will be posted on this coming Wednesday?If you would like to advertise in the CCO please contact us City-County [email protected] “Readers Poll” question is: Do you feel that the main stream media failed in reporting the real facts concerning the 2014 SBOA audits short falls of the City of Evansville?Copyright 2015 City County Observer. All rights reserved. This material may not be published, broadcast, rewritten or redistributedFacebookTwitterCopy LinkEmail
As of 5 p.m. Friday, the contrast between the rebuilt beaches at 56th Street and 57th Street and the eroded beach at 58th Street is dramatic. Check OCNJ Daily for updates and photos of the Ocean City beach replenishment project for 2015 in the south end between 37th and 59th Streets.DATE: Friday, Sept. 4PROGRESS: As of Friday at 5 p.m., the advancing edge of the project area is just north of the 58th Street beach entrance walkway. The beaches at 56th Street and 57th Street are closed, though it’s likely the 56th Street beach entrance will reopen on Saturday.Beaches between 37th Street and 55th Street are now complete, and the pipeline feeding that part of the project has been removed.WHAT’S NEXT: Work will continue in the area between 55th Street and 59th Street in the final phase of the project. Sand-pumping is expected to be complete within another week or two. Dune crossover work will follow. And the planting of dune grass is scheduled for November.READ MORE: Ocean City NJ Beach Replenishment 2015 Daily UpdateFOR DAILY UPDATES by E-MAIL: Sign up for free
== WENDEL ==What’s new?Danish machinery firm Diosna has developed a new kneading tool for its Wendel Mixer, distributed in the UK by Benier. This allows bakers to process batches of dough requiring just one-third of the mixing bowl’s capacity. Anything from 160kg to 600kg of dough can now be processed and it can handle up to 5,000kg of dough an hour.OK, but what are the other benefits of a Wendel?Patience! The mixer has two kneading tools installed off-centre. As they turn in opposite directions, the kneading action encourages rapid development with minimal shear damage and low temperature gain.What about efficiency?You are tough to please! Standard UK mixers tend to have a ’dead’ area beneath the mixing posts or centre columns which may reduce the yield, but the Wendel doesn’t.Does Diosna have any other mixing options?Its recently launched PSPVW Spiral Mixer has special tooling, that combines the functions of a classic mixer with beating machines and planetary mixers. This allows it to stir, mix and beat in pastes, batters, creams and butter for cakes and desserts.www.benier.co.uk== SANCASSIANO ==Impress me!Alright, here goes. Traditionally, the dough for high-volume biscuit plants is produced using horizontal mixers, but the clever engineers at Italian firm Sancassiano have come up with a swanky ’double force’ vertical mixer with two mixing tools. The fully automatic 800kg batch system can handle up to 10 tonnes of dough an hour.What’s all that about?Horizontal mixers do not allow mixing action flexibility. But the Sancassiano Vertical Mixer enables you to change mixing tools depending on the dough, thanks to a quick-lock tool changeover device. It is suitable for biscuit doughs for wire-cut, depositing, rotary moulding or rotary cutting, as well as for cracker doughs.Keep going.Working more frequently with smaller batches lessens the amount of moisture lost from the dough during processing. Vertical Mixers are also gentle on delicate inclusions such as choc chips.What outputs can it handle?The machine is sold as a unit mixer with 200kg to 800kg batch bowl sizes and can be set into a carousel operation. A robotic version can produce up to 10 tonnes of dough per hour.Sancassiano is represented in the UK and Ireland by Sollich UK.www.sollich.co.uk== AQUAMIX ==What’s the latest?The Aquamix, designed by VMI to knead highly-hydrated doughs, has a flat-bottom bowl, fitted with a half-twist expanded spiral and a round centre post, with a scraper. This means it kneads without sticking. Good news for ciabatta and focaccia producers.I’m a control freak.No problem. The Aquamix is fitted with a frequency variator allowing bakers to change the kneading intensity according to the water percentage of the dough. This allows the mixing profiles of recipes to be personalised. Its touchscreen control panel can store up to 99 recipes.What if I’m into cakes?Optional interchangeable tools means the Aquamix can be changed from a spiral mixer to one with a flat beater, suitable for mixing cake and muffin batters. An all-stainless steel option is also available for high-risk operations.Tell me more about VMI.The firm supplies craft and plant bakers with removable bowl spiral and double spiral mixers with individual dough batch capacities up to 900kg. Automated mixing solutions range from 500kg to 1,500kg per hour. European Process Plant supplies the mixers in the UK and Ireland.www.europeanprocessplant.com== BAKER PERKINS ==Why so excited?There’s a new control system for Tweedy mixers from Baker Perkins, designed for both standard and pressure-vacuum mixers. It has clearer, more intuitive graphics, better recipe management and upgraded historical data trending. This all helps enhance quality and consistency in the final product.I see. Any more details?Sure. The system offers intelligent alarm handling, including suggested actions to guide operators to the source of problems. Simpler communication also enhances the recipe and schedule management for plants with multiple mixers.Sounds like a big project.Not as big as you might think. To minimise installation times Baker Perkins has significantly reduced site wiring, and software interfaces are tested prior to shipping to site.What else should I know?Baker Perkins says the Tweedy can mix 14 batches of dough an hour (up to 5,400kg). The pressure-vaccuum model improves oxidisation leading to better product texture and colour and can be used to vary texture from very small cell size to more open structures.www.bakerperkinsgroup.com
Marko Josipovic, a bakery and patisserie student at University College Birmingham and a Dawn Foods student ambassador, on how to make your bakery photos stand out online. ”As a bakery student and keen food photographer, I often post photos of my creations on my Instagram feed @Marko_bakes.When I started my food photography and food blogging journey, I just had an iPhone 4 and an old wooden table. I would take photos of food, not really caring about what was in the whole photo. Soon I learned that it wasn’t the camera that was doing the bad job, it was me.You don’t need fancy camera equipment, especially if you’re just starting out. Get a few nice plates, paint a wall white, or invest in a good backdrop, and you’re set.Here are some of my top tips:Tip 1 – LightingI always use natural light, taking photos right next to the window of my kitchen. However, make sure that when you are taking photos, you look through the camera’s eyes first, and see how the lighting actually looks in the photo.Tip 2 – Styling and angleAs a rule of thumb, I have three different angles from which I like to shoot: the overhead angle, the 45-degree angle, and straight on.The overhead angle is great for desserts, where you want to show off shapes, symmetry, or patterns.I usually use the 45-degree angle if I want to show depth or highlight a specific part of the dessert, such as a bite out of a sheet cake.The straight-on angle is great for stacks of foods, such as cookies or pancakes, and it’s great for capturing drips or drizzles.Tip 3 – PracticeYou’ll never get an amazing photo on your first try, but if you keep trying and researching bloggers to see what they’re doing, you’ll adapt, learn and, eventually, find your own style of photography.Also, never underestimate the power of a good filter. Editing photos is my favourite part of food photography. I am not very skilful in Photoshop, so I use editing apps on my phone to edit my photos. The app I use most is called ‘A Color Story’, but I also use ‘Lightroom’ with it.Once you edit that photo and it looks even better than you expected, that’s when the magic happens.”